Meet the Keller family, five generations of firstborn women - an unbroken line of daughters - living together in the same house on a secluded olive grove in the Sacramento Valley of Northern California. Anna, the family matriarch, is 112 and determined to become the oldest person in the world. An indomitable force, strong in mind and firm in body, she rules Hill House, the family home she shares with her daughter Bets, granddaughter Callie, great-granddaughter...

Single mom Shandi Pierce's life takes a turn when an enigmatic geneticist saves her and her 3-year-old genius son from an armed robber.